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(3-EXO)-3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yloxy)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane

Development stage
Unknown
Modality
Small Molecules
01

Overview

This compound is a synthetic small molecule belonging to the dibenzocycloheptene class of organic compounds and features a polycyclic aromatic hydrocarbon structure with an azoniabicyclic moiety[2][10]. It is also known as N-methyldeptropine and has been referenced in chemical databases under several code names including CHEMBL1946187 and DB07494[1][2]. The drug has not been approved for any indication and is classified as experimental with no reported clinical trials or approved uses to date[2]. Its mechanism of action is not explicitly described in public sources; however, based on its structural similarity to other tropane derivatives such as deptropine or benztropine analogs—which are known muscarinic acetylcholine receptor antagonists—it may act on cholinergic pathways but this remains speculative.

Other names
N-Methyldeptropine(1R,3S,5S)-8,8-dimethyl-3-(tricyclo(9.4.0.03,?)pentadeca‑1(11),3,5,7,12,14-hexaen‑2‑yloxy)‑8‑azabicyclo[3.2.1]octan‑8‑ium(1R,3S,5S)-8,8-dimethyl–3-{tricyclo[9.4.0.03.?]pentadeca–1(11), 3 , 5 , 7 , 12 , 14–hexaen–2–yloxy}–8–azabicyclo[3 .2 .1 ] octan – 8 – ium(3-exo)-3-(10,11-Dihydro‐5H‐dibenzo[a,d][7]annulen‐5‐yloxy)‐8 , 8 ‑ dimethyl ‑ 8 ‑ azoniabicyclo [ 3 .2 .1 ] octane(1R , 3R , 5S ) -  dimethyl - { tricyclo [9 .4 .0 .03 ,? ] pentadeca - (15 ),  hexaen - yloxy } - azabicyclooctan - ium
02

Targets

Nicotinic Acetylcholine Receptor

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